ACN neuro EXTRA STRENGTH

Neurological Healing and Brain Function Support

SCIENCE

Alpha-GPC

A: http://examine.com/supplements/alpha-gpc/#citations Alpha-glycerophosphocholine (Alpha-GPC or α-GPC) is a cholinergic compound that is used for its cognitive-promoting properties, and to enhance power output in athletes. It appears to also support cellular membranes, and may aid in preventing cognitive decline. Over 20 studies involving more than 5,000 patients have shown that Alpha-GPC increases alertness, boosts learning, and revitalizes mental performance. Studies also show it improves memory and mental clarity in people with severe mental decline.

CDP-choline (citicholine)

B: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548494/ Dietary CDP-choline supplementation prevents memory impairment caused by impoverished environmental conditions in rats.

Study conclusion: These findings indicate that long-term dietary CDP-choline supplementation can ameliorate the hippocampal-dependent memory impairment caused by impoverished environmental conditions in rats, and suggest that its actions result, in part, from a long-term effect such as enhanced membrane phosphatide synthesis, an effect shown to require long-term dietary supplementation with CDP-choline.

General: http://examine.com/supplements/CDP-choline/

Bacopa (Bacopa monnieri)

C: http://online.liebertpub.com/doi/abs/10.1089/rej.2013.1431 This review synthesizes behavioral research with neuromolecular mechanisms putatively involved with the low-toxicity cognitive enhancing action of Bacopa monnieri (BM), a medicinal Ayurvedic herb. BM is traditionally used for various ailments, but is best known as a neural tonic and memory enhancer. Numerous animal and in vitro studies have been conducted, with many evidencing potential medicinal properties. Several randomized, double-blind, placebo-controlled trials have substantiated BM’s nootropic utility in humans. There is also evidence for potential attenuation of dementia, Parkinson’s disease, and epilepsy.

  • Study conclusion: Current evidence suggests BM acts via the following mechanisms—anti-oxidant neuroprotection (via redox and enzyme induction), acetylcholinesterase inhibition and/or choline acetyltransferase activation, β-amyloid reduction, increased cerebral blood flow, and neurotransmitter modulation (acetylcholine [ACh], 5-hydroxytryptamine [5-HT], dopamine [DA]).

Study: http://link.springer.com/article/10.1007%2Fs11064-011-0681-1  Bacopa monnieri (L.) is a revered medicinal plant of traditional Indian system of medicine effective against cognitive impairment in ageing and SDAT. In our previous study, long term administration of bacosides was found to exhibit remarkable anti-aging effect, ameliorate age associated neurochemical and neurobehavioral deficits and prevent hippocampal neuronal degeneration in middle aged and aged rat brain cortex.

  • Study conclusion: Thus, the present results suggest that bacosides possess immense potential to act as a neuroprotective agent due to its pleiotropic action for the prevention of ageing complications and SDAT progression.

General: http://examine.com/supplements/Bacopa+monnieri/

Theanine (L-Theanine)

D: http://examine.com/supplements/Theanine/ L-Theanine, for the most part, is a relaxing but not sedating amino acid that is synergistic with stimulants such as caffeine as it can ‘take the edge off’. It is effective by itself in the standard supplemental dosages as well, and although it can be attained via a diet high in green tea ingestion that is the only dietary source of L-Theanine. The properties of L-theanine can be summed up as being a relaxing agent without sedation (relative to something like lemon balm which relaxes but may also sedate), and is also implicated in reducing the perception of stress and slightly improving attention.

Ginseng (Panax ginseng)

E: http://www.ncbi.nlm.nih.gov/pubmed/26161118 The effect of ginseng (Panax ginseng) berry ethyl acetate fraction (GBEF) on mice with high-fat diet-induced cognitive impairment was investigated to confirm its physiological function.

  • Study conclusion: The in vivo experiments showed that mice treated with GBEF exhibited more improved cognitive behavior than DM mice.

Study: http://www.ncbi.nlm.nih.gov/pubmed/25535479 Ginseng has been shown to exert antistress effects both in vitro and in vivo.

  • Study conclusion: Collectively, the data indicate that KRG represses oxidative stress-induced apoptosis by enhancing PI3K/Akt signaling via upregulation of ER-β expression.

Study: http://www.sciencedirect.com/science/article/pii/0378874186900632 A double-blind, placebo-controlled clinical study on the effect of a standardized ginseng extract on psychomotor performance in healthy volunteers.

  • Study conclusion: It is concluded that G 115 may be superior to placebo in improving certain psychomotor functions in healthy subjects.

Sage (Salvi officinalis)

F: http://www.ncbi.nlm.nih.gov/pubmed/21553931 With a longstanding reputation in European herbal encyclopedias for improving memory, Salvia officinalis L. or S. lavandulifolia Vahl. have a range of relevant neurobiological activities:

Study conclusion: in vitro—antiAChE [28,29] and anti-BuChE activities [46]; anti-inflammatory and estrogenic activities [47]; antioxidant effects [24]; antiamylodogenic activity [48]; and in vivo—anti-AChE [49]; and memory enhancement [50]. In both young and elderly normal volunteers sage enhances memory (including accuracy of immediate recall).

Study: http://www.nature.com/npp/journal/v31/n4/abs/1300907a.html Effects of Cholinesterase Inhibiting Sage (Salvia officinalis) on Mood, Anxiety and Performance on a Psychological Stressor Battery

Study conclusion: The results confirm previous observations of the cholinesterase inhibiting properties of S. officinalis, and improved mood and cognitive performance following the administration of single doses to healthy young participants.

Study: http://www.sciencedirect.com/science/article/pii/S0091305703001229 Salvia lavandulaefolia (Spanish Sage) enhances memory in healthy young volunteers

Study conclusion: These results represent the first systematic evidence that Salvia is capable of acute modulation of cognition in healthy young adults.

Study: http://www.nature.com/npp/journal/v31/n4/abs/1300907a.html Effects of Cholinesterase Inhibiting Sage (Salvia officinalis) on Mood, Anxiety and Performance on a Psychological Stressor Battery

Study conclusion: The results confirm previous observations of the cholinesterase inhibiting properties of S. officinalis, and improved mood and cognitive performance following the administration of single doses to healthy young participants.

Tumeric (Curcuma longa)

G: http://www.ncbi.nlm.nih.gov/pubmed/21473798  Chronic dietary supplementation with turmeric protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-mediated neurotoxicity in vivo: implications for Parkinson’s disease.

Study conclusion: Further characterization of the active constituents of turmeric that potentially promote neuroprotection could improve the utility of dietary turmeric in brain function and disease.

Ginkgo (Ginkgo biloba)

H: http://www.pnas.org/content/98/12/6577.short Extracts of Ginkgo biloba leaves are consumed as dietary supplements to counteract chronic, age-related neurological disorders.

  • Study conclusion: This study reveals that diets supplemented with Ginkgo biloba extract have notable neuromodulatory effects in vivo and illustrates the utility of genome-wide expression monitoring to investigate the biological actions of complex extracts.

Study: http://onlinelibrary.wiley.com/doi/10.1111/j.1755-5949.2010.00202.x/pdf There are far more mechanistic and clinical data on Ginkgo biloba relevant to dementia than for any other plant species. This may reflect the widespread use of ginkgo for many conditions other than memory.

Study conclusion: Favorable effects on cerebral circulation, neuronal cell metabolism, the cholinergic system; has antioxidant activity, reduces apoptosis, and is neuroprotective against NO- and β-amyloid-induced toxicity; the latter effect is associated with the flavonoids.

Magnesium

I: http://examine.com/supplements/Magnesium/ Magnesium is an essential dietary mineral, and the second most prevalent electrolyte in the human body. Magnesium deficiencies are common in developed countries. A deficiency increases blood pressure, reduces glucose tolerance and causes neural excitation.

http://archneur.jamanetwork.com/article.aspx?articleid=565793#Abstract The Nervous system is influenced greatly by alterations in the concentration of the major cations in the extracellular fluid. The neurological manifestations of disorders of calcium, sodium, and potassium metabolism have been rather well defined. There are also considerable data which demonstrate that derangement of the metabolism of magnesium, the body’s fourth most abundant cation, also profoundly affects the nervous system.

Zinc

J: http://jn.nutrition.org/content/130/2/347S.short Low consumption of foods rich in bioavailable iron (Fe) and zinc (Zn) such as meat, particularly red meat, and high consumption of foods rich in inhibitors of Fe and Zn absorption, such as phytate, certain dietary fibers and calcium, cause Fe and Zn deficiencies. Neuropsychologic impairment is one of several potential outcomes of these deficiencies.

http://www.nature.com/nrn/journal/v6/n6/abs/nrn1671.html

Peppermint (Mentha x piperita)

K: http://onlinelibrary.wiley.com/doi/10.1002/ptr.3037/abstract With the aim of investigating potential central nervous system (CNS) activities of traditional medicinal plants, four species and one hybrid of the genus Mentha (M. aquatica, M. longifolia, M. pulegium, M. suaveolens and M. × piperita) were selected.

  • Study conclusion: All the plants exhibited antioxidant and MAO-A inhibitory activities, M. × piperita being the most active. M. aquatica showed the highest affinity to the GABAA-receptor assay. Results demonstrate that mints might have effect on the CNS.

Source: http://www.advancedbionutritionals.com/Production/Health-Alert/HAL/201507/Advanced-Memory-Formula-ABFSLNK1375.htm

Features & Benefits:

  • ACN Neuro Extra Strength is the results of many years research providing valuable nutrients directed specifically towards neurological health.
  • For best results, use ACN Neuro Extra Strength with ACS 200 Extra Strength and ACZ nano Extra Strength for total body nutrition, cleansing and rejuvenation.
  • ACN Neuro Extra Strength improves memory, alertness, improves mood, cognitive performance, psychomotor functions and mental clarity and increases cerebral blood flow; also reduces mental anxiety and stress.
  • Simple to use, just spray, swish and swallow, has a pleasant taste with a hint of natural mint.
  • This formula is created using a proprietary selective nutrient extraction process that derives the most out of the ingredients, delivering the power of each ingredient in the most effective manner possible, achieving maximum results, without stomach discomfort or other side effects.
  • Alpha-GPC Alpha-glycerophosphocholine: Alpha-GPC is a very unique compound that is used for its cognitive-promoting properties. It appears to also support cellular membranes, and may aid in preventing cognitive decline. Over 20 studies involving more than 5,000 patients have shown that Alpha-GPC increases alertness, boosts learning, and revitalizes mental performance. Studies also show it improves memory and mental clarity in people with severe mental decline. (A: see Results RNA Extra Support for ACN Neuro Extra Strength)
  • CDP-choline (citicholine): CDP-choline has been shown to exhibit excellent cognitive improvement in those taking it. If that wasn’t a good enough reason to take CDP-choline, for all of us with a seemingly never ending list of things to do, CDP-choline has also been shown to improve focus. And with even more benefits, as we age CDP-choline has also been shown to reduce the rate of memory decline. All you have to do is remember to take ACN Neuro Extra Strength. (B: see Results RNA Extra Support for ACN Neuro Extra Strength)
  • Bacopa (Bacopa monnieri): Bacopa is a very interesting ingredient that is prescribed in ancient Indian Ayuvedic medicine. In recent studies, supplementing Bacopa monnieri has been shown to improve Cognition by reducing Anxiety; something we can all use. It is also reliable for improving Memory formation. Though memory effects are usually studied in older adults, Bacopa monnieri appears to affect young people as well. Bacopa monnieri interacts with the dopamine and serotonergic systems, but its main mechanism concerns promoting neuron communication. It does this by enhancing the rate at which the nervous system can communicate by increasing the growth of nerve endings, a valuable benefit indeed. Bacopa monnieri is also an antioxidant. (C: see Results RNA Extra Support for ACN Neuro Extra Strength)
  • Theanine (L-Theanine): Theanine is a uniquely relaxing amino acid found in ACN Neuro Extra Strength that has the ability to calm the mind without putting you to sleep. And if you do drink caffeinated beverages, Theanine takes the edge off without reducing your energy levels. Theanine has also been implicated in reducing the perception of stress and slightly improving attention. (D: see Results RNA Extra Support for ACN Neuro Extra Strength)
  • Ginseng (Panax ginseng): The benefits of supplementing Ginseng have been known for centuries, with the ability to improve cognition and reduce stress. Gineng has been shown to improve physical skills such as coordination, dexterity, grace, strength, and speed. These are referred to as psychomotor skills. When it comes to improving our coordination we can all use a little more grace and a little more Ginseng in our stride. (E: see Results RNA Extra Support for ACN Neuro Extra Strength)
  • Sage (Salvi officinalis): Another proven ingredient, Sage has a long history in European herbal encyclopedias for improving memory, and provides a range of relevant neurobiological activities. The first on the list is memory enhancement, something we can’t get enough of. Studies using Sage have been shown to improve the memory in both young and elderly volunteers. This includes long term memory and the accuracy of immediate recall. Sage has also been shown to improve mood and cognitive performance in healthy, young study participants. (F: see Results RNA Extra Support for ACN Neuro Extra Strength)
  • Tumeric (Curcuma longa): Tumeric is a remarkable spice with many healthful benefits. In promoting neurological health, a study in 2011 concluded that dietary consumption of tumeric protects the brain against neurotoxic damage, with potential application towards neurodegeneration. (G: see Results RNA Extra Support for ACN Neuro Extra Strength)
  • Ginkgo (Ginkgo biloba): Ginkgos are large trees, normally reaching a height of 66–115 feet, with some specimens in China being over 164 feet and being recorded as thousands of years old. Extracts of Ginkgo biloba leaves are consumed as dietary supplements to counteract chronic, age-related neurological disorders. Interestingly, there is far more clinical data on Ginkgo biloba relevant to dementia than for any other plant species. This may reflect the widespread use of ginkgo for many neurological uses including memory. (H: see Results RNA Extra Support for ACN Neuro Extra Strength)
  • Magnesium: We’ve all heard of Magnesium. What you might not know is just how important Magnesium is for supporting your health. Magnesium is an essential dietary mineral, and the second most prevalent electrolyte in the human body. And yet, Magnesium deficiencies are common even in developed countries. Magnesium deficiency increases blood pressure, reduces glucose tolerance and causes neural excitation. The Nervous system is influenced greatly by deficiencies in the concentration of the major positively charged ions in the fluid outside of the cells. Studies show that the imbalance of the metabolism of magnesium, the body’s fourth most abundant positively charged ion, also profoundly affects the nervous system. We all need Magnesium. Magnesium should be taken daily and is found in ACN Neuro Extra Strength. (I: see Results RNA Extra Support for ACN Neuro Extra Strength)
  • Zinc: The use of zinc in medicinal skin cream was mentioned in Egyptian papyri from 2000 BC. With more and more research coming forth regarding the number of biological functions, health implications and pharmacological targets that are emerging for zinc indicate that it might turn out to be ‘the calcium of the twenty-first century’. We all need Zinc and it’s also found in ACN Neuro Extra Strength. (J: see Results RNA Extra Support for ACN Neuro Extra Strength)
  • Peppermint Leaf (Mentha x piperita):The ancients certainly were aware of the mint family’s medicinal value, having been used as herbal medicines in ancient Egypt, Greek and Rome thousands of years ago. Dried peppermint leaves have even been found in several Egyptian pyramids carbon dating back to 1,000 BC. Today, modern scientific investigations are revealing an abundance of potential health benefits associated with the use of different components of the peppermint plant, including aromatherapeutic, topical and internal applications which might have an effect on the Central Nervous System. (K: see Results RNA Extra Support for ACN Neuro Extra Strength)
  • Customers who use ACN Neuro Extra Strength claim improved memory, alertness and feelings of well being.
  • ACN Neuro Extra Strength optimizes reflexes and motor responses.
  • ACN Neuro Extra Strength results are fast acting and safe.
  • Usually significant benefit can be felt within the first few hours of product use.
  • Continual use provides increased and continual benefit.
  • ACN Neuro Extra Strength has no side effects.
DOSAGE GUIDELINES

Standard Dose

Take 6 sprays by mouth, twice daily.

Higher Dose

Take 12 sprays by mouth, twice daily.

Optimal Use

  • Spray, swish and swallow. You may take other Results RNA formulas immediately.
  • Do not eat or drink for 2 minutes following.
SUPPLEMENT FACTS

SERVING SIZE

Serving size: 12 Sprays

Servings Per Container (2oz/60mL): Approx. 30
Servings Per Container (4oz/120mL): Approx. 60

AMOUNT PER SERVING
Proprietary Blend Tincture 250 mg*

INGREDIENTS

Ingredients

Alpha-glycerophosphocholine (Alpha-GPC), CDP-choline (citicholine), Bacopa (Bacopa monnieri), L-Theanine, Ginseng (Panax ginseng), Sage (Salvia officinalis), Tumeric (Curcuma
longa), Ginkgo biloba, Magnesium, Zinc, Peppermint Leaf (Mentha x piperita) and Natural Trace Minerals.

Other Ingredients: Ultra-Pure Deionized Water

* % Daily value not established

BEST RESULTS

For Best Results:

Take ACN neuro Extra Strength with ACS 200 and ACZ nano Extra Strength to achieve optimal nervous system support and total body detoxification.

Improves Memory and Mental Clarity
ACN neuro Extra Strength is a uniquely effective neurological health formula with ingredients shown to improve memory, boost alertness, increase cognitive performance and more.*

Supports the Nervous System
As diseases such as Lyme or Alzheimer’s progress, they can attack the nervous system, producing learning disabilities, mood swings, memory loss, anxiety and depression, panic attacks, obsessive behavior, and other psychiatric diagnoses. ACN neuro reduces mental anxiety and stress; specifically on brain cells while reducing neuroinflammation.*

Acts as a Neuroprotector
ACN neuro supports the central nervous system, providing clinically proven ingredients shown to counteract chronic, age-related neurological disorders.

Reduces Anxiety and Stress
Both anxiety and stress cause a cascade of chemical reactions within the brain. ACN neuro increases cerebral blood flow; while reducing mental anxiety and stress.*

2 oz $29.95
4 oz $49.95

Clinically Proven Results
Over 20 studies involving more than 5,000 patients have shown that Alpha-GPC increases alertness, boosts learning, and revitalizes mental performance. Studies also show it improves memory and mental clarity in people with severe mental decline.

Improves the Neuro-Psychiatric
ACN neuro supports psychomotor functions, mental clarity and enhances mood. Customers who use ACN Neuro Extra Strength claim improved memory, alertness, and improved feelings of well-being.*

Neurological System Rejuvenation
ACN neuro Extra Strength effectively reduces neurological manifestations such as severe brain fog. Results are fast acting and safe.

Advanced Cellular Technology
ACN neuro delivers the power of each ingredient in the most effective manner possible; achieving maximum results without stomach discomfort or side effects. With Advanced Cellular Technology, ACN neuro Extra Strength Intra-oral spray is immediately absorbed, simple to take, and has a pleasant taste with a hint of natural mint. Just spray, swish, and swallow.*

Ingredients

Alpha-glycerophosphocholine (Alpha-GPC), CDP-choline (citicholine), Bacopa (Bacopa monnieri), Theanine (L-Theanine), Ginseng (Panax ginseng), Sage (Salvia officinalis), Tumeric (Curcuma longa), Ginkgo biloba, Magnesium, Zinc, Peppermint Leaf (Mentha x piperita) with Advanced Cellular Minerals.

Other Ingredients: Ultra-Pure Deionized Water

Offered in 2 oz and 4 oz Intra-oral Sprays

* % Daily value not established

Directions for Use

Directions for Use: Take 6 sprays twice daily for health maintenance or 12 sprays twice daily for heightened support.

Take each formula individually by mouth, swish and then swallow. The formulas can be taken in any combination without waiting in between dosing and can be taken with food or without, at any time of the day. Always remain well hydrated when taking the sprays.

2 oz formula: Provides 30 days of support when administered at the standard dose (6 sprays, twice daily).
4 oz formula: Provides 60 days of support when administered at the standard dose (6 sprays, twice daily).

Purity and Quality Guaranteed:

gmp_logoACN neuro Extra Strength is produced under strict GMP manufacturing controls in conformance with guidelines for dietary supplements set forth in USP XXVII.For purity and quality, ACN neuro contains no preservatives • no alcohol • no artificial coloring or flavoring. For customer support, please call 1 888 823 3869.